OSTEOPOROSIS DRUGS FACTS

The Untold Truth About Osteoporosis Drugs

These “wonder drugs” that the media has hyped to the unsuspecting public? The newest and most widely prescribed drugs recently approved by the FDA for treatment of osteoporosis are alendronate, a biophosphanate which is marketed under the brand name Fosamax®, synthetic calcitonin marketed under the brand name MiacalcinTM, raloxifene, marketed as Evista®, and the most recent drug risedronate Sodium, marketed as Actonel™. Let’s take a brief look at these drugs, the claims being made for their efficacy, and the potential damage these “wonder drugs” can inflict.

Alendronate

Alendronate is the first nonhormonal osteoporosis drug to be approved by the FDA for use in the United States. It is sold by Merck and Company, Inc. Researchers say it works by binding to the bone that has been targeted by bone-eating osteoclasts, thereby protecting it from being broken down. They claim women using the drug in pharmaceutical company studies lost one-third less height, and suffered 50% fewer fractures than those taking calcium alone.

Although it is not clear how, researchers also claim the drug can increase bone mass. In one study, women using alendronate appeared to have their spines thickened by three percent a year during the course of a three year study.

The downside to the drug appears to be four-fold in nature:

1. It happens that the drug must be used for a long period of time to gain maximum benefit – possibly for as long as 20 years on a daily basis, and perhaps for the remainder of the patient’s life in serious cases of the disease.
2. The side effects of long-term use of the drug are completely unknown – the drug was only tested for three years. As Dr. Bruce Ettinger, Senior Researcher at Kaiser Permanent Medical Program in Northern California
   has stated,“We don’t have a clue as to its long-term safety. I would be extremely cautious before giving it to a 50-year old who hasn’t started to experience fractures.” At least some of the drug stays in the bone forever,
   even if use of the drug is halted. Again, potential long-term side effects of this drug in the human body are completely unknown.
3. Gastrointestinal problems are common with use of this drug. People using Alendronate must subscribe to a strict set of restrictions and rules when taking the drug. For example, he must stay upright and active for at least
   30 minutes after taking a dose to keep his stomach acids from causing potentially serious injury to the esophagus. Other risks and benefits are currently unknown.
4. The drug is expensive.

Calcitonin

Calcitonin is a hormonal drug that appears to slow down bone-eating osteoclasts. It has been used successfully in the U.S. for more than a decade, but only in an injectable form that did not gain many adherents due to the necessity of taking painful shoots in the thigh on a daily basis. Now the drug is available in a more convenient nasal spray. Researchers claim that although the injectable form has “very few” side effects, the spray form is only half as ffective as Alendronate, resulting in bone mass gains of only one and a half percent per year, during the course of a twoyear
study.

Potential side effects that were until recently not clearly spelled out for those already taking the drug include headache, dizziness, anorexia, diarrhea, skin rashes, and edema (swelling). The nasal spray has additional side effects of nose bleeds, sinusitis, and inflammation of the nasal membranes.

Because Calcitonin is a protein, a large number of people taking the drug over a longer period of time may develop a resistance to it or experience an allergic reaction. Further, long term use can hurt your pocketbook because Calcitonin, like Alendronate, is expensive.

Raloxifene

Another new drug on the market is Raloxifene, (sold under the brand name Evista®). This is the first drug in a new class of drugs called Selective Estrogen Receptor Modulators, who purport to provide estrogen-like benefits of bone and heart protection, while doing away with estrogen negatives breast and uterine stimulation.

Evista® does show real promise in stopping bone loss, but between its restrictions and side effects, it does not prove to be a healthy alternative. Raloxifene can only be used in postmenopausal women. It works much like estrogen in stopping and preventing bone loss but it does not stop any other menopausal side effects nor does it act like an estrogen in any other ways.

In fact, Raloxifene can cause hot flashes and blood clots in many patients. Patients using this drug must move about or exercise regularly to prevent the blood clots. There are many other painful, uncomfortable and often debilitating side effects. Raloxifene is not approved in Canada and has conflicting test results in its ability to prevent fractures, especially those occurring in the spine, without increasing cancer risks.

Simply put Raloxifene is a risky therapy choice with little being known about its long-term affects or benefits.

Even while appearing to circumvent many of the negative side-affects of hormone replacement therapy, Raloxifene still carries with it many potentially harmful effects that patients should be concerned about.

Like Hormone Replacement Therapy (HRT), Raloxifene does produce an increase in the incidence of deep
venous thrombosis (blood clots), along with a slightly increased risk of hot flashes. What’s more, like estrogen therapy, the drug produces effects on lipid metabolism that are very similar to estrogen. Data on the increased risk of cardiovascular and cerebrovascular disease is still being studied.

Risedronate Sodium

This most recently approved drug (sold under the brand name Actonel™) has been shown to slow bone loss, increase bone density, and reduce spine and nonspine fractures. While testing on this new product are still being conducted, the negative factors associated with this drug are already evident.

Most inconveniently, Actonel must be taken first thing in the morning, on an empty stomach, with a plain glass of
water. The patient must then remain upright for at least one half hour, and refrain from eating, drinking, or taking other medications for at least 30 minutes.

The Real Problem With These Drugs

The real problem with these drugs is that neither of them comes anywhere near to addressing the actual cause of osteoporosis. Instead of helping stop osteoporosis, they directly interfere with the body’s own natural process. In other words, the underlying cause of the osteoporosis still exists. But the drugs unnaturally repress the body’s responses to these underlying causes in an effort to stop the resulting bone loss.

From our point of view, it is this unnatural repression of the body’s natural response to systemic malfunction that makes the drugs so undesirable. If the same problem could be dealt with and reversed naturally, without repressing the body’s responses to the underlying problem, then that should be the preferred form of therapy.

But for the big pharmaceutical companies there are no billion dollar profits to be made in unpatentable “natural remedies” – however effective they may be. Therefore, instead of a safe, all-natural preparation, you get powerful hormones and drugs (which have known cancer risks and/or unknown long-term side effects) as the only alternative to the suffering from this dreaded disease.

In reality, osteoporosis is not caused by a lack of the drug Alendronate. Nor is it caused by a lack of the hormonal drug Calcitonin, Raloxifene, or Risedronate Sodium. Yet the orthodox medical establishment continues to put forth drugs like these as “cures” for the disease, when in reality they are only makeshift or stopgap measures that must be used forever, and potentially dangerous ones at that.

Introducing OsteOrganiCAL®

The Amazing Osteoporosis Discovery!

A great number of extraordinary remedies and cures have come out of the Amazon rainforest over the past few decades. So many, that today teams of medical and science researchers from countries around the world are pouring through the rain forest cataloging medicinal plants, and studying their rich chemical compositions in hopes of discovering even more potential cures for some of mankind’s most debilitating illnesses.

But while the vast majority of these hardy researchers are still looking inward toward the rain forests for the next big cure, a small number of farsighted researchers have turned to coastal waters, searching and studying aquatic plant-life for its potential medicinal value. Remarkably, in the case of osteoporosis, one research team appears to have hit pay dirt.

How it Happened

The OsteOrganiCAL® story begins in 1979 when an oceanographer became intrigued by the numerous cases and unusual severity of rachitis, or rickets, in several local populations. Rickets is a debilitating mineral deficiency disease
that chiefly affects children during the period of skeletal growth. It is usually characterized by soft and deformed bones, and is caused by the body’s failure to assimilate and use calcium and phosphorus due to inadequate sunlight or vitamin D3 intake.

Aware of the phenomenal mineral content of certain “green foods” such as chlorella and spirulina algaes, the oceanographer gathered samples of a particular form of algae he had discovered.The well known Antoine
Berberian, M.D., biochemist and scientific researcher, contacted the researchers who were already working on the rickets problem.

The oceanographer explained his idea that the algae might be high enough in natural mineral content to be used to help alleviate the mineral deficiency causing rickets. Dr. Berberian and his research team were immediately interested and went to work studying the unique form of algae. First, they conducted tests on the toxicology of the algae. After finding it safe, they conducted additional tests on the potential nutritive value of the algae.

The initial results were so encouraging that the prestigious research team quickly began widening its scope of research. Soon, they began looking into the algae’s potential as an effective allnatural therapy for osteoporosis.The reason was that the algae contained a unique, highly absorbable form of calcium – an oxide organic calcium that proved to be nusually absorbable in the human body.

90% Absorbable!

In fact, whereas a typical form of calcium such as calcium carbonate might achieve 7-8% absorption by the human body, and special forms of calcium might achieve 30-40% absorption, this unique “sea algae calcium” proved to be a stunning 90% absorbable by the human body.

The research team discovered that the algae contained perfectly balanced amounts of magnesium and manganese – the very minerals now known bymedical science to be crucial to absorption, metabolism and utilization of calcium in the uman body.

Furthermore, the researchers discovered that because of its amazing rate of absorption, high doses of the calcium weren’t necessary to achieve significant gains in bone mass in individuals given the algae. The algae‘s low natural calcium concentrations worked perfectly.

The Vitamin D3 Breakthrough

This extraordinary discovery prompted the doctors to double their research efforts on the algae. Knowing that most people suffering from even moderate osteoporosis were usually seriously deficient in Vitamin D3 (the essential hormonal form of Vitamin D without which calcium cannot be used by the body for bone formation), the researchers decided to add the vitamin to the processed algae.

They knew that naturally occurring vitamin D3 could be taken from fish oil, so they began tests on several of the large variety of sharks. What they discovered was surprising. When formulated with the calcium-containing algae, the naturally occurring vitamin D3 from the shark oil dramatically improved calcium’s ability to solidify as new bone mass. Not only did the new formulation halt osteoporosis better and faster, but the researchers began observing bone mass increases as high as 3% in as little as three to six months, and 18% increases after being on OsteOrganiCAL® for nearly 15 months.

This is an extremely significant achievement considering that the expensive osteoporosis “wonder drugs” approved by the FDA could only produce small increases in bone mass, one up to 3% per year, but another produced only half that uch. Evista® has been shown to prevent bone loss, but the effect is not as powerful as hormone replacement therapy. This means you’d have to wait anywhere from two to eight times longer with the mainstream drugs to get the same results produced by OsteOrganiCALs® all-natural algae formulation. Furthermore, none of the “wonder drugs” achieved bone mass increases through safe, natural means; none of them do anything to address the underlying metabolic cause of osteoporosis; and all of them exhibit unwanted side effects.

Beats the “Wonder Drugs” Hands Down!

The final formulation is so effective it only requires daily supplementation or about six months to two years depending on the case of osteoporosis and as little as two-three months per year in subsequent years as a maintenance program. Compare this to “wonder drugs” approved by the FDA, which have to be taken daily for years on end (and perhaps forever) to maintain their effectiveness, and you’ll see why we’re so excited about this remarkable all-natural reakthrough.

95% Success Rate!

It’s now been over 20 years since Dr. Berberian began working with OsteOrganiCAL® ... Dr. Berberian has carried out over 300 separate treatment studies on osteoporosis sufferers in private facilities, official
institutions, and municipal healthcare programs.

According to the researcher, of these 300 treatment studies, the only instances in which the formulation did not work were in a very small percentage of cases (only 5%) where the osteoporosis was caused by complications of cancer or other serious illnesses. In 95% of all treatment studies, significant bone mass increase was achieved in the patients.

We find the results of these studies extraordinary indeed. For example, in one instance, the patient achieved bone mass increases of 4.8% in the hip and 4.4% in areas of the spine – in only four months. These amazing increases were ocumented by sophisticated bone densitometry tests utilizing dual photon x-ray absorptiometry, and were conducted by an independent medical study center.

What Doctors Have to Say About OsteOrganiCAL®

“My clinical results in reversing ostopenia and osteoporosis have been better than those obtained using Fosamax®.”

— W. Ward, M.D. North Carolina

“I have used OsteOrganiCAL® on a number of patients. The majority had increased their bone density in their dexa-scan
after six months to one year.”

— K.Hothner M.D., Florida

Letters From Grateful OsteOrganiCAL® Users

Here are brief excerpts from several letters we’ve graciously been given permission to reprint. Individuals who have recently tried OsteOrganiCAL® and later wrote the manufacturer to express their surprise at its effectiveness.

“I am pleased with the results as far as pain is concerned. I used to have a spot on the side of my foot, which hurt on the side of my foot, which hurt quite a lot when walking, and that pain is pretty well gone, also, the surgery area feels just fine now too. Plus, I feel better after being on this product. My doctor would have preferred that I take Fosamax®, but after much deliberation, was convinced I should try OsteOrganiCAL®, for which I am grateful to you and my Lord.”

– Arleen B. Watseki, IL

“This is my second order and I feel so much better after two months of taking OsteOrganiCAL®.”

— Rogene L., Fort Worth, TX

“I find that if I stop taking OsteOrganiCAL®, I get the pain back. If I continue taking it, I am fine.”

— Emma H. Hollywood, FL

" This year from January through March I was again in bed. I ordered OsteOrganiCAL® in March. Within two weeks I was
better and in two more weeks I was even better and in two more weeks the sciatic pain left. I have been on it for 8 onths
now and haven’t been in bed for 7 months.”

— Ruby D., Banks, OR “

I can tell you that I can hardly believe that my left knee is beginning to tell me that it is recovering, no hurts or pain. It is recovering so well that I hardly know that I have a knee. This is an absolutely wonderful product. I am so glad that I opted for OsteOrganiCAL® instead of Fosamax®. I am not near a bone scanner at this time, but I certainly don’t feel like a cripple.”

— M.S., Kansas

“In April I had a bone scan and was diagnosed with severe osteoporosis. In May I found out about a product called OsteOrganiCAL®, I took OsteOrganiCAL® for three months, went and had another bone scan. My overall bone density was increased 3.9%. I have never felt better.”

— Joan M. Wilton Manors, FL

“I first started on it nearly two months ago and my back feels so much more relaxed. Thank you for the first improvement I
Page 7 have seen in 23 years.”

— Mary P., Arvada, CO

“I am so delighted with your OsteOrganiCAL® program. I have been on this product for 5 months. I have osteoporosis and rheumatoid arthritis. I am 67 years old. When I first started taking your product, my lower back was very weak, also
my legs, especially the knees, were very weak. I can see a lot of difference now, after 5 months. Last month I had a hard fall, my hip was black and purple. My chiropractor said she had never seen any bruise that bad, without a broken hip. I am sure it was the Natural Option Product that saved me from a break. Thank you so much for stronger bones.”

— Nancy L. Punta Gorda, FL

“Please find enclosed the results of 2 DEXA bone density tests, the first indicating severe osteoporosis. Although Fosamax® has been strongly recommended, I have put off taking it in favor of trying OsteOrganiCAL® and weight bearing exercises. My second bone density test having taken OsteOrganiCAL® for almost 6 months by the time. Test results indicated a 3.5% increase in lumbar spine density. Needless to say, I am very pleased with the increase.

— Martha B. Phoenix, AZ

“I have been using OsteOrganiCAL® for a year with good results. The technician, after the second scan, told me that I ad improved by 7% which she felt was impressive. I have learned a valuable lesson to pass along to others.”

— Margaret C., Vista, CA

“My first bone density test indicated I was at risk for traumatic fracture. After I began the OsteOrganiCAL® program, my follow-up test showed considerable improvement.”

— Doris W., Raleigh, NC

“ . . . after taking my first 6 months of OsteOrganiCAL®, and seeing the results of the bone density test, I showed them to my endocrinologist . . . He was delighted and said, “Never before have I seen such an improvement in an 80-year- old woman.”

— Audrey C. Timonium, MD

“I am very pleased with this product and will continue taking it. My doctor is amazed. I recently received a copy of my bone density report. I have discontinued Fosamax® for a year. The report still showed improvement.”

— Carla S., St. Louis, MO

“I have dutifully taken the product since it arrived some weeks back. The soreness of my lower back has diminished
considerably despite my getting even less lower back exercise than I was before.”

— Susan K. Sun Valley, CA